01 - Preheat oven to 350°F. Grease and line a 9x5-inch loaf pan with parchment paper.
02 - Whisk together flour, baking powder, baking soda, and salt in a medium bowl. Set aside.
03 - Using an electric mixer or whisk, beat butter and granulated sugar until light and fluffy.
04 - Incorporate eggs one at a time, mixing well after each addition.
05 - Mix in lemon zest, lemon juice, and vanilla extract until combined.
06 - Alternately add flour mixture and milk to the wet ingredients, starting and ending with the flour. Stir gently until just combined, avoiding overmixing.
07 - Pour batter into prepared pan and smooth the surface evenly.
08 - Bake for 45 to 55 minutes, or until a toothpick inserted into the center comes out clean.
09 - Allow loaf to cool in the pan for 10 minutes, then transfer to a wire rack to cool completely.
10 - Whisk powdered sugar with fresh lemon juice until smooth and pourable.
11 - Drizzle glaze over cooled loaf and let it set before slicing and serving.